Compound Record - 3-hydroxybutyrate

Name 3-hydroxybutyrate
Formula C4H8O3
HMDB ID HMDB0000011
Synonyms 3-HB ; 3HB ; 3-hydroxybutyrate ; 3-hydroxybutyric acid ; beta-hydroxybutyrate ; beta-hydryoxybutyric acid ; B-HB ; BHB
  • 3-hydroxybutyrate Peak Groups
  • 3-hydroxybutyrate Peak Data

    • 3-hydroxybutyrate used as a tracer
  • Peak Groups
  • Peak Data
  • Fcirc Data

    • List of Animals using 3-hydroxybutyrate as a tracer compound
    Animal Studies Genotype Infusate Tracer Compound(s) Tracer(s) Tracer Concentration(s) (mM) Tracer Elements Infusion Rate (ul/min/g) Treatment Body Weight (g) Age (weeks) Sex Diet Feeding Status Sample Owners Total Tissues Total Samples Total MSRuns
    col005g_01 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 31.0 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_02 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 29.8 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_03 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 26.0 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_04 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 26.8 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_05 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 24.8 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_06 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 25.6 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_07 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 26.0 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_08 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 27.3 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_09 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 24.4 14 M LabDiet 5010 fasted Marc Bornstein 7 9 9
    col005g_10 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 26.0 14 M LabDiet 5010 fasted Marc Bornstein 7 9 15
    col005g_11 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 no treatment 28.7 14 M LabDiet 5010 fasted Marc Bornstein 7 9 15
    col005g_12 Cold Exposure C57BL/6J 3-hydroxybutyrate-[13C4][25]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 25.0 C 0.1 cold 4C acute 27.6 14 M LabDiet 5010 fasted Marc Bornstein 7 9 15
    WDL_20220307_M1 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 32.0 C 0.1 no stress 25.8 12 M PicoLab Rodent 20 5053 None Won Dong Lee 1 1 4
    WDL_20220307_M2 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 32.0 C 0.1 no stress 25.1 12 M PicoLab Rodent 20 5053 None Won Dong Lee 1 2 8
    WDL_20220310_M4 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32];L-cystine-[13C6,15N2][28];asparagine-[13C4,15N2][3.5];malate-[13C4][1.2];taurine-[13C2,15N1][11]
    malate, 3-hydroxybutyrate, asparagine, taurine, L-cystine
    malate-[13C4], 3-hydroxybutyrate-[13C4], asparagine-[13C4,15N2], taurine-[13C2,15N1], L-cystine-[13C6,15N2]
    		 1.2, 32.0, 3.5, 11.0, 28.0 C, C+N 0.1 no stress 23.9 12 M PicoLab Rodent 20 5053 None Won Dong Lee 1 1 4
    WDL_20220318_M2_02 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32];L-cystine-[13C6,15N2][28];asparagine-[13C4,15N2][3.5];malate-[13C4][1.2];taurine-[13C2,15N1][11]
    malate, 3-hydroxybutyrate, asparagine, taurine, L-cystine
    malate-[13C4], 3-hydroxybutyrate-[13C4], asparagine-[13C4,15N2], taurine-[13C2,15N1], L-cystine-[13C6,15N2]
    		 1.2, 32.0, 3.5, 11.0, 28.0 C, C+N 0.1 no stress 26.3 12 M PicoLab Rodent 20 5053 None Won Dong Lee 1 2 8
    WDL_20220401_M1_01 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32];L-cystine-[13C6,15N2][28];asparagine-[13C4,15N2][3.5];malate-[13C4][1.2];taurine-[13C2,15N1][11]
    malate, 3-hydroxybutyrate, asparagine, taurine, L-cystine
    malate-[13C4], 3-hydroxybutyrate-[13C4], asparagine-[13C4,15N2], taurine-[13C2,15N1], L-cystine-[13C6,15N2]
    		 1.2, 32.0, 3.5, 11.0, 28.0 C, C+N 0.1 no stress None 12 M PicoLab Rodent 20 5053 None Lingfan Liang 1 1 4
    WDL_20220408_M5 Acute Stress C57BL/6N 3-hydroxybutyrate-[13C4][32];L-cystine-[13C6,15N2][28];asparagine-[13C4,15N2][3.5];malate-[13C4][1.2];taurine-[13C2,15N1][11]
    malate, 3-hydroxybutyrate, asparagine, taurine, L-cystine
    malate-[13C4], 3-hydroxybutyrate-[13C4], asparagine-[13C4,15N2], taurine-[13C2,15N1], L-cystine-[13C6,15N2]
    		 1.2, 32.0, 3.5, 11.0, 28.0 C, C+N 0.1 no stress 24.4 12 M PicoLab Rodent 20 5053 None Won Dong Lee 1 2 8
    XZ.fasted.[U-13C] 3-hydroxybutyrate.xz307 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][40]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 40.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 fasted Xianfeng Zeng 11 12 12
    XZ.fasted.[U-13C] 3-hydroxybutyrate.xz308 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][40]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 40.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 fasted Xianfeng Zeng 11 11 11
    XZ.fasted.[U-13C] 3-hydroxybutyrate.xz309 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][40]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 40.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 fasted Xianfeng Zeng 11 11 11
    XZ.refed.[U-13C] 3-hydroxybutyrate.xz387 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][60]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 60.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 refed Xianfeng Zeng 12 12 12
    XZ.refed.[U-13C] 3-hydroxybutyrate.xz388 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][60]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 60.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 refed Xianfeng Zeng 11 11 11
    XZ.refed.[U-13C] 3-hydroxybutyrate.xz389 fluxomics 2020 C57BL/6 3-hydroxybutyrate-[13C4][60]
    3-hydroxybutyrate
    3-hydroxybutyrate-[13C4]
    		 60.0 C 0.1 no treatment None 13 M PicoLab Rodent 20 5053 refed Xianfeng Zeng 12 12 12