List of Studies
| Study | Description | Genotypes | Infusates | Tracer Compound(s) | Tracer Elements | Treatments | Sample Owners | Total Infusates | Total Animals | Total Tissues | Total Samples | Total MSRuns |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aging Fluxomics | Metabolic homeostasis in young and aged mice | C57BL/6J | C | no treatment | Melanie McReynolds |
1 Infusate |
16 | 19 | 281 | 281 | ||
| Arterial enrichment | None | C57BL/6 | C | no treatment | Won Dong Lee |
3 Infusates |
12 | 1 | 12 | 12 | ||
| Chronic Cold Exposure | Double-catheterized mice were placed in 4C or room temperature (~22C) housing without food at ZT2. Length of infusion varied depending on tracer, but all infusions concluded at ZT8 for a total of 6 hours cold exposure. Study performed by Marc Bornstein (Arany Lab) and LCMS by Michael Neinast (Rabinowitz Lab). | C57BL/6J | C | cold 6C chronic, thermoneutrality chronic | Marc Bornstein |
1 Infusate |
11 | 1 | 22 | 88 | ||
| Cold Exposure | Double-catheterized mice were placed in 4C or room temperature (~22C) housing without food at ZT2. Length of infusion varied depending on tracer, but all infusions concluded at ZT8 for a total of 6 hours cold exposure. Study performed by Marc Bornstein (Arany Lab) and LCMS by Michael Neinast (Rabinowitz Lab). | C57BL/6J | C, H | no treatment, cold 4C acute | Marc Bornstein | 84 | 10 | 711 | 1348 | |||
| fluxomics 2020 | Steady-state infusions in wildtype mice that were fasted or refed. Published by lead authors Tony Hui and Alexis Cowan in https://doi.org/10.1016/j.cmet.2020.07.013 | C57BL/6 | lactate-[13C3][490],
lactate-[13C3][390],
glutamine-[13C5][100],
alanine-[13C3][200],
alanine-[13C3][300],
3-hydroxybutyrate-[13C4][40],
3-hydroxybutyrate-[13C4][60],
C16:0-[13C16][4],
C16:0-[13C16][10],
C18:1-[13C18][4],
lactate-[13C3][0],
glutamine-[13C5][0],
glucose-[13C6][400],
glucose-[13C6][200] |
C | no treatment | Sheng Hui, Zhaoyue Zhang, Tara TeSlaa, Xianfeng Zeng |
14 Infusateslactate-[13C3][490],
lactate-[13C3][390],
glutamine-[13C5][100],
alanine-[13C3][200],
alanine-[13C3][300],
3-hydroxybutyrate-[13C4][40],
3-hydroxybutyrate-[13C4][60],
C16:0-[13C16][4],
C16:0-[13C16][10],
C18:1-[13C18][4],
lactate-[13C3][0],
glutamine-[13C5][0],
glucose-[13C6][400],
glucose-[13C6][200]
|
60 | 20 | 842 | 769 |